Hormonal causes of recurrent pregnancy loss (RPL)

Nicola Pluchino, Panagiotis Drakopoulos, Jean Marie Wenger, Patrick Petignat, Isabelle Streuli, Andrea Riccardo Genazzani

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Endocrine disorders play a major role in approximately 8% to 12% of recurrent pregnancy loss (RPL). Indeed, the local hormonal milieu is crucial in both embryo attachment and early pregnancy. Endocrine abnormalities, including thyroid disorders, luteal phase defects, polycystic ovary syndrome …

Extensive personal experience. Validation of prolactin levels in menstrual disorders and in prolactinomas

Menelaos L. Batrinos

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It is now well established that hyperprolactinaemia is not rare and in the majority of cases is caused by a pituitary tumor, a prolactinoma. However, despite a plethora of relevant publications there are still certain questions that have not been adequately addressed: 1. What is the upper normal level of serum prolactin beyond which the condition should be characterized as hyperprolactinaemia …