Ioannis Kyrou, Constantine Tsigos
Chronic stress represents a prolonged state of dyshomeostasis caused by intense and frequently imposed stressors. Obesity constitutes a chronic dysmetabolic state, leading progressively to a spectrum of metabolic complications, such as diabetes, dyslipidemia, hypertension and cardiovascular disease. Α growing body of evidence supports the existence of significant interactions between stress and obesity …
Menelaos L. Batrinos
Clusters of poorly demarcated neurons, called nuclei, situated in the hypothalamic area are the source of hormones which through the succession of their actions on the pituitary and the peripheral endocrine glands, regulate and control major functions …
Christos Tsatsanis, Eirini Dermitzaki, Pavlina Avgoustinaki, Niki Malliaraki, Vasilis Mytaras, Andrew N. Margioris
Adipose tissue produces factors, including adipokines, cytokines and chemokines which, when released, systemically exert endocrine effects on multiple tissues thereby affecting their physiology. Adipokines also affect the hypothalamic-pituitary-gonadal (HPG) axis both centrally, at the hypothalamic-pituitary level …