Expression of somatostatin receptors may guide the use of somatostatin receptor imaging and therapy in differentiated thyroid cancer

Giorgio Treglia, Guido Rindi, Vittoria Rufini

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Thyroid carcinoma is the most frequent type of endocrine tumour. Most differentiated thyroid cancers (DTCs) have an excellent prognosis if diagnosed early and treated appropriately. Nevertheless, a number of patients with DTCs do not achieve remission after thyroidectomy …

Novel Approaches to the Management of Graves` Ophthalmopathy

Luigi Bartalena, Maria Laura Tanda, Alessandra Medea, Claudio Marcocci, Aldo Pinchera

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Severe Graves’ ophthalmopathy constitutes a complex therapeutic challenge and treatment outcome often is not satisfactory. Established methods of treatment include high-dose glucocorticoids, orbital radiotherapy and orbital decompression. Recently, the use of intravenous glucocorticoids has been shown to provide more favorable results than oral glucocorticoids…

Therapeutic trends and outcome of acromegaly: a single center experience over a 40-year period

Olga Karapanou, Marinella Tzanela, Marietta Christoforaki, Lida Papastathopoulou, Paraskevi Moutsatsou, Efi Botoula, Stylianos Tsagarakis

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OBJECTIVE: To evaluate the therapeutic trends and long-term outcome of treatment modalities for acromegaly in our center over a 40-year period. Design: We retrospectively studied 321 acromegalic patients (145 males/176 females) diagnosed and treated from the 1970s until September 2013 …