Yuji Hiromatsu, Hiroshi Satoh, Nobuyuki Amino
Hashimoto’s thyroiditis (HT), a common thyroid disease, is now recognized as an autoimmune thyroid disorder (AITD). However, surprisingly little is known about its discoverer, Hakaru Hashimoto, who first described the disease in 1912 …
Ulla Feldt-Rasmussen, Åse Krogh Rasmussen
Coexistence of differentiated thyroid cancer (DTC) and thyroid autoimmune diseases could represent a mere coincidence due to the frequent occurrence of autoimmunity, but there may also be a pathological and causative link between the two conditions. The coincidence of DTC with Hashimoto’s disease has been variably reported …
Rosaria Maddalena Ruggeri, Paola Minciullo, Salvatore Saitta, Salvatore Giovinazzo, Rosaria Certo, Alfredo Campennì, Francesco Trimarchi, Sebastiano Gangemi, Salvatore Benvenga
OBJECTIVE: Hashimoto’s thyroiditis (HT) is considered to be a Th1-related autoimmune disease (AID). Recent studies revealed that Th17 lymphocytes (producing mostly IL-17, IL-21 and IL-22) play a major role in numerous AIDs commonly thought to be Th1 diseases. More recently, another subset of Th cells …
Giulia Cogni, Luca Chiovato
Autoimmune diseases are a group of heterogeneous disorders characterized by abnormal lymphocytic activation directed against self-tissues. Hashimoto’s thyroiditis (HT) and Graves’ disease (GD) are two of the most common clinical expressions of organ-specific autoimmunity …
Elias E. Mazokopakis, Anastasios A. Tzortzinis, Elpida I. Dalieraki-Ott, Athanasios N. Tsartsalis, Periklis K. Syros, Christos M. Karefilakis, Maria G. Papadomanolaki, Ioannis K. Starakis
OBJECTIVE: The association between Hashimoto’s thyroiditis (HT) and papillary thyroid carcinoma (PTC) remains controversial in medical bibliography. The main objective of our study was to determine the prevalence of PTC and HT coexistence in histopathologic material of thyroidectomized patients. DESIGN: In a retrospective study …
Gianluca Tamagno, Gadintshware Gaoatswe
Encephalopathy associated with autoimmune thyroid disease is a rare condition presenting in the setting of autoimmune thyroid disease and characterized by unspecific neurological and/or psychiatric symptoms. Bearing in mind the currently prevailing lack of consensus on the most appropriate nomenclature and diagnostic criteria for this condition and the implications …
Dohee Kim
OBJECTIVE: The association of low vitamin D status with autoimmune thyroid disease (AITD), which includes Hashimoto’s thyroiditis (HT) and Graves’ disease (GD), is controversial. The aim of this study was to investigate the correlation between vitamin D insufficiency and AITD, HT, and GD. DESIGN: Our cross-sectional study included patients …
Teresa Zak, Anna Noczýnska, Renata Wasikowa, Urszula Zaleska-Dorobisz, Anna Golenko
The aim of the study was to analyze data related to chronic autoimmune thyroid disease at diagnosis and at follow-up of children and adolescents in Lower Silesia in the years 1999-2004. Age, gender, incidence of thyroid disease in the family, clinical presentation, hormonal findings, levels of thyroid antibodies, results of ultrasonography, and fine needle aspiration biopsy (FNAB) were recorded …
Panayota Kolypetri, Natasha A. Noel, Karen A. Carayanniotis, George Carayanniotis
OBJECTIVE: In NOD.H2h4 mice, high dietary iodine intake has been known to cause Iodine-accelerated Spontaneous Autoimmune Thyroiditis (ISAT) via an unknown mechanism. The aim of the study was to examine whether the NOD.h4 genetic background predisposes to enhanced iodine organification in thyroglobulin …
Sripathy Gopalakrishnan, Sourav Sen, Jawahar Singh Adhikari, Pradeep Kumar Chugh, Tarun Sekhri, Sankar Rajan
OBJECTIVE: Autoimmune Thyroid Disease (AITD) results from an interaction of exogenous and endogenous factors in a genetically predisposed individual. AITD is being increasingly reported among the Indian population. Lymphocyte subsets and levels of interleukin-5 (IL- 5) were studied in the peripheral blood of patients with AITD …
Vaitsa Giannouli, Konstantinos A. Toulis, Nikolaos Syrmos
ΟBJECTIVE: Although overt hypothyroidism has been documented as exerting detrimental effects on cognition and behavior, it remains controversial whether subclinical hypothyroidism or euthyroid patients with Hashimoto’s thyroiditis (HT) under levothyroxine (LT4) treatment …