Lymphocytes T-Helper 17 and 22 (Th17 and Th22)

Serum interleukin-22 (IL-22) is increased in the early stage of Hashimoto’s thyroiditis compared to non-autoimmune thyroid disease and healthy controls

Posted on by

Rosaria Maddalena Ruggeri, Paola Minciullo, Salvatore Saitta, Salvatore Giovinazzo, Rosaria Certo, Alfredo Campennì, Francesco Trimarchi, Sebastiano Gangemi, Salvatore Benvenga

Download PDF

OBJECTIVE: Hashimoto’s thyroiditis (HT) is considered to be a Th1-related autoimmune disease (AID). Recent studies revealed that Th17 lymphocytes (producing mostly IL-17, IL-21 and IL-22) play a major role in numerous AIDs commonly thought to be Th1 diseases. More recently, another subset of Th cells …