Hormones in pain modulation and their clinical implications for pain control: a critical review

Xueyin Chen, Jinyuan Zhang, Xiangrui Wang

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Recently, more and more studies have found that pain generation, transmission and modulation are under hormonal regulation. Indeed, hormonal dysregulation is a common component of chronic pain syndromes. Studies have attempted to determine whether the relationship between the pain and its perception and hormones is a causative relationship and how these processes interrelate …

The Sertoli cell as the orchestra conductor of spermatogenesis: spermatogenic cells dance to the tune of testosterone

Fotios Dimitriadis, Chara Tsiampali, Nikolaos Chaliasos, Panagiota Tsounapi, Atsushi Takenaka, Nikolaos Sofikitis

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Spermatogenesis is contingent upon hormones and growth factors acting through endocrine and paracrine pathways either in vivo or in vitro. Sertoli cells (SCs) furnish essential factors for the successful advancement of spermatogenesis and spermiogenesis. Moreover, receptors for follicle stimulating hormone (FSH) and testosterone …

Hormones, hormonal agents, and neuropeptides involved in the neuroendocrine regulation of sleep in humans

Grigorios Kotronoulas, Antonios Stamatakis, Fotini Stylianopoulou

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Sleep is an essential ubiquitous biological process, a periodical state of quiescence in which there is minimal processing of sensory information and no interaction with conspecifics or the environment. Despite relevant research on sleep structure and testing of numerous endogenous sleep-affecting chemicals, questions as to the precise mechanisms …

The response of serum leptin, cortisol and zinc concentrations to concurrent training

Guilherme Rosa, Estelio H.M. Dantas, Danielli Braga de Mello

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OBJECTIVE: To investigate the effects of concurrent training (CT) on serum leptin, cortisol and zinc concentrations in physically active adults. DESIGN: Ten subjects aged (27.1±4.8 years, BMI 25.49 ± 2.65) were recruited to participate in three sessions: control session (CS), concurrent training 1 (CT1) and concurrent training 2 (CT2) sessions with five days of resting between them. In each session blood samples for leptin …

Relationship between salivary and serum testosterone levels in response to different exercise intensities

Amy R. Lane, Anthony C. Hackney

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The anabolic hormone testosterone (T) continues to be researched extensively in exercise studies, with blood serum or plasma samples collected routinely. This method is considered both valid and reliable; however, the collection process can be invasive and difficult during exercise …