Thyroid involvement in hepatitis C – Associated mixed cryoglobulinemia

Poupak Fallahi, Silvia Martina Ferrari, Dilia Giuggioli, Andreina Manfredi, Caterina Mancusi, Silvia Fabiani, Marco Centanni, Santino Marchi, Clodoveo Ferri, Alessandro Antonelli

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OBJECTIVE: The prevalence and clinical features of thyroid involvement in patients with hepatitis C virus-associated mixed cryoglobulinemia (MC+HCV) have been reviewed. DESIGN: A PubMed Medline search was conducted through December 2011 to identify all studies that reported thyroid involvement …

Thyroid autoimmunity and miscarriage

Athina Kaprara, Gerasimos E. Krassas

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The relation of thyroid autoimmunity to miscarriage is an important issue that has attracted the interest of many investigators. A number of papers have been published so far, which include healthy women, women with recurrent miscarriage and those undergoing assisted reproductive techniques. Most studies have shown a significant positive association between the presence of thyroid autoantibodies and miscarriage rate…

An overview of the pathogenesis of thyroid autoimmunity

Giulia Cogni, Luca Chiovato

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Autoimmune diseases are a group of heterogeneous disorders characterized by abnormal lymphocytic activation directed against self-tissues. Hashimoto’s thyroiditis (HT) and Graves’ disease (GD) are two of the most common clinical expressions of organ-specific autoimmunity …

Molecular parameters linking thyroglobulin iodination with autoimmune thyroiditis

George Carayanniotis

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Increased iodide intake has been linked to the development of hypothyroidism and/or autoimmune thyroiditis in humans and animals, but the mechanisms involved remain poorly understood. Increased ingestion of iodide is likely to have pleiotropic effects on either metabolic or immunological processes. Within the latter domain, recent interest has been focused on two areas …

Increased primary autoimmune thyroid diseases and thyroid antibodies in sarcoidosis: evidence for an under-recognised extrathoracic involvement in sarcoidosis?

Foteini Malli, Alexandra Bargiota, Kathrin Theodoridou, Zoi Florou, Fotini Bardaka, George N. Koukoulis, Konstantinos I. Gourgoulianis, Zoe Daniil

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OBJECTIVE AND DESIGN: Sarcoidosis has been associated with thyroid diseases. However, until today no definite conclusions have been drawn. We aimed to assess the frequency of thyroid disorders and the levels of thyroid hormones and thyroid antibodies in 68 sarcoidosis patients and 75 controls …

L-carnitine treatment in a seriously ill cancer patient with severe hyperthyroidism

Rene Chee, Ravin Agah, Roberto Vita, Salvatore Benvenga

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OBJECTIVE: To report a case of vaccine-induced Graves’ disease successfully managed with L-carnitine and propranolol and without antithyroid drugs (ATDs). ATDs sometimes need to be used at low doses or can be contraindicated/refused. One of the ancillary compounds available is L-carnitine …