The role of iodine in the evolution of thyroid disease in Greece: from endemic goiter to thyroid autoimmunity

Stelios Fountoulakis, George Philippou, Agathocles Tsatsoulis

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The thyroid gland is dependent on dietary iodine for the production of thyroid hormones, normal iodine requirement being about 150-200μg/day. Long-term deficiency in iodine intake is associated with the development of goiter. When the prevalence of goiter in a population rises above 5-10%, the problem is considered endemic …

Endemic Goiter – an update

Demetrios A. Koutras

“Goiter” means thyroid enlargement, and “endemic” means frequent in a certain locality. The problem is from what volume and up a thyroid is considered to be large enough as to be classified as goiter and also from what prevalence and up an area is considered to be endemic. It is obvious that by playing with these definitions one may increase or decrease …

Iodine and differentiated thyroid cancer: Pathogenetic and therapeutic implications*

Smyth Peter, Cloughley George, Clarke Cathy, Smith Derek, Burbridge Emma

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The purpose of this review is to discuss the various means by which iodine ingestion through dietary intake or therapeutic administration can influence the pathogenesis, prevalence, presentation or outcome of differentiated thyroid cancer (DTC). The relationship between iodine nutrition and DTC pathogenesis is complex …

No increase in renal iodine excretion during pregnancy: a telling comparison between pregnant women and their spouses

Eftychia Koukkou, Stavros Kravaritis, Irene Mamali, Georgios G. Markantes, Marina Michalaki, Georgios G. Adonakis, Neoklis A. Georgopoulos, Kostas B. Markou

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OBJECTIVE: Adequate dietary iodine intake is necessary for normal thyroid gland function at all times, and most particularly during pregnancy. Increased iodine loss is cited, among other factors, as responsible for the increased iodine demand in this period. Our aim was to compare renal iodine excretion between …

The Republic of Srpska Iodine Deficiency Survey 2006

Amela Lolic, Νenad Prodanovic

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Objective: A survey related to iodine deficiency in the Republic of Srpska was first conducted in 1999 and resulted in the adoption of regulations concerning the quality of salt for human consumption. In order to reassess iodine status, we conducted the Republic of Srpska Iodine Deficiency Survey in 2006 …

Relationship between serum zinc levels, thyroid hormones and thyroid volume following successful iodine supplementation

Sibel Ertek, Arrigo FG Cicero, Oya Caglar, Gurbuz Erdogan

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OBJECTIVE: Zinc is essential for many biochemical processes and also for cell proliferation. Thyroid hormones influence zinc metabolism by affecting zinc absorption and excretion. Additionally, zinc deficiency affects thyroid function. The aim of the present study was to evaluate a possible association of zinc levels with thyroid volume …