The response of corticotropin and adrenal steroids to desmopressin stimulation in patients with various forms of hypercortisolism

Eugenia I. Marova, Nikolay P. Goncharov, Galina S. Kolesnikova, Svetlana D. Arapova, Anastasiya M. Lapshina

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OBJECTIVE: The purpose of this study was to evaluate the direct action of desmopressin (agonist of vasopressin) on the hypophysis and the three zones of the adrenal cortex in patients with different forms of hypercortisolism. DESIGN: Forty-three patients with hypercortisolism—21 with Cushing’s disease (14 females, 7 males), 11 with extrapituitary …

Cushing’s syndrome in pregnancy: Report of a case and review of the literature

Marina Kita, Maria Sakalidou, Athanasios Saratzis, Sarris Ioannis, Avraam Avramides

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Cushing’s syndrome (CS) during pregnancy is a rare nosology with only a few cases reported in the literature. Misdiagnosis is common, as the syndrome may be easily confused with preeclampsia or gestational diabetes. CS during pregnancy is usually associated with severe maternal and fetal complications..

Atypical presentation of a hormonally active adrenocortical tumor in an adolescent leading to delayed diagnosis

Kerstin Hagemann, Maura Zanolari Calderari, Aurel Perren, Ian Cree, Primus E. Mullis, Christa E. Flück

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Adrenocortical tumors are rare in children and present with variable signs depending on the type of hormone excess. We herein describe the unusual presentation of a child with adrenocortical tumor and introduce the concept of in vitro chemosensitivity testing. CASE REPORT: A 10.5-year-old girl presented with hypertrichosis/hirsutism and weight loss …