Detection rate of somatostatin receptor PET in patients with recurrent medullary thyroid carcinoma: a systematic review and a meta-analysis

Giorgio Treglia, Adriana Tamburello, Luca Giovanella

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PURPOSE: Several articles have demonstrated the high diagnostic performance of somatostatin receptor positron emission tomography (PET) in patients with neuroendocrine tumours (NETs). On the other hand, only a few studies have evaluated the detection rate (DR) of this imaging method in recurrent medullary thyroid carcinoma (MTC). We aimed to perform a systematic review and a meta-analysis of the DR of somatostatin receptor PET or PET/CT in patients with recurrent MTC to add evidence-based data …

Persistent hyperinsulinemic neonatal hypoglycemia caused by focal nesidioblastosis. Preoperative diagnosis by pancreatic venous sampling

Maria Maniati-Christidis, Fotini Psychou, Claire Nihoul-Fekete

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A female infant with persistent hyperinsulinemic hypoglycemia is described. Persistent euglycemia could not be achieved by diazoxide, somatostatin and frequent, low protein feeds. Preoperative localization of focal insulin hypersecretion by percutaneous pancreatic venous sampling allowed excision of only a small pancreatic portion which was followed by normalization of blood glucose levels …