Genovefa D. Kolovou, Vana Kolovou, Demosthenes B. Panagiotakos, Ioannis Vasiliadis, Vassiliki Giannakopoulou, Peggy M. Kostakou, Vassiliki Vartela, Sophie Mavrogeni
OBJECTIVE: In the present study, we evaluated the influence of lipoprotein lipase (LPL) and apolipoprotein (apo) E polymorphisms on lipid concentrations of 178 Greek men of similar age with coronary heart disease (CHD), but varying body mass index (BMI). DESIGN: Patients were divided according to their BMI …
Eugen Melcescu, Michael Griswold, Lianbin Xiang, Sheila Belk, Denise Montgomery, Marilyn Bray, Kevin S. Del Ben, Gabriel I. Uwaifo, Gailen D. Marshall, Christian A. Koch
OBJECTIVE: Polymorphisms (SNP) in the glucocorticoid receptor (GR) gene can alter sensitivity to glucocorticoids. Previous studies of the N363S and BclI SNP in the GR gene have shown a metabolic syndrome phenotype in mostly non-African populations. The obesity phenotype of African Americans …
Nectaria Xita, Leandros Lazaros, Ioannis Georgiou, Agathocles Tsatsoulis
OBJECTIVE: Insulin resistance is a key factor in the pathogenesis of polycystic ovary syndrome (PCOS). Peroxisome proliferator-activated-receptor-γ (PPAR-γ) has been implicated in insulin resistance and adiposity. The aim of the study was to investigate the possible involvement of the Pro12Ala polymorphism …