Weightlessness and skeleton homeostasis

Konstantinos Ziambaras1, Roberto Civitelli2, Stathis S. Papavasiliou1 1Department of Endocrinology, University of Crete Medical School, Iraklion, Grete, Greece, 2Division of Bone and Mineral Diseases, Washington University School of Medicine, St Louis MO, USA Abstract As human beings venture into space in the 21st century, they will be confronted with a "hypodynamic" and thus hostile environment Read More

Advanced glycation end products and diabetic complications: A General overview

Melpomeni Peppa, Helen Vlassara Division of Experimental Diabetes and Aging, Department of Geriatrics, Mount Sinai School of Medicine, NY, NY 10029, USA Abstract Diabetes mellitus, especially type 2 diabetes is increasing at an alarming rate reaching epidemic proportions. Although hyperglycemia has been considered as playing an important role in the pathogenesis of diabetic complications, the Read More

Applications of genomic medicine in endocrinology and post-genomic endocrine research

Constantine A. Stratakis Heritable Disorders Branch, and the Section on Endocrinology & Genetics, Developmental Endocrinology Branch, (DEB), National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD 20892, USA Abstract In the mid 1980's, two advances revolutionized Medicine in a way that is comparable only to some of the Read More

Chronic autoimmune thyroid disease in children and adolescents in the years 1999-2004 in Lower Silesia, Poland

Teresa Zak1, Anna Noczýnska1, Renata Wasikowa1, Urszula Zaleska-Dorobisz2, Anna Golenko1 1Chair and Clinic of Endocrinology and Diabetology in the Developmental Age, University of Medicine, Wroclaw, Poland, 2Department of Radiology University of Medicine, Wroclaw, Poland Abstract The aim of the study was to analyze data related to chronic autoimmune thyroid disease at diagnosis and at follow-up Read More

Improved somatic growth following adenoidectomy and tonsillectomy in young children. Possible pathogenetic mechanisms

Harilaos S. Vontetsianos1, Spiros E. Davris1, George D. Christopoulos1, Catherine Dacou-Voutetakis2 1ENT Department and 2Endocrine Unit, First Paediatric Department, Athens University, Children's Hospital "Agia Sophia" Athens, Greece Abstract The effect of Adenotonsillectomy on somatic growth was studied prospectively in 57, randomly selected children (31 boys, 26 girls), aged 5.03±1.32 (mean±1SD) years. The indication for surgery Read More

Of Temples and Plane Trees: the Hippocratic Legacy as Collective Memory

Gerasimos P. Sykiotis1, George D. Kalliolias2, Christos Terezis2, Athanasios G. Papavassiliou3 1Department of Biomedical Genetics, University of Rochester Medical Center, Rochester NY, USA, 2Department of Philosophy, School of Humanities & Social Sciences, University of Patras, Patras, Greece, 3Department of Biochemistry, School of Medicine, University of Patras, Patras, Greece In the homeland of Hippocrates, the study Read More

Exercise and the Stress System

George Mastorakos1, Maria Pavlatou1, Evanthia Diamanti-Kandarakis2, George P. Chrousos3 1Endocrine Unit, Second Department of Obstetrics and Gynecology, Aretaieion Hospital, 2Endocrine Section, First Department of Medicine, Laiko Hospital, 3First Department of Pediatrics, "Agia Sophia" Children's Hospital, Athens University Medical School, Athens, 115 27, Greece Abstract Exercise represents a physical stress that challenges homeostasis. In response to Read More

Polycystic ovary syndrome. Revised diagnostic criteria and long-term health consequences

Eleni Kousta, George Tolis, Stephen Franks Ippokration Hospital, Athens, Greece (G.T.), Institute of Reproductive & Developmental Biology Imperial College London, Hammersmith Hospital, London U.K. (S.F.) Abstract The diagnostic criteria for polycystic ovary syndrome (PCOS) have recently been revised. The polycystic ovarian morphology has been introduced as part of the criteria and an international consensus has Read More

Growth hormone binding protein and acid labile subunit levels in the assessment of acromegaly treatment

Marinella Tzanela, Marieta Christoforaki, Lida Papastathopoulou, Dimitra Vassiliadi, Effie Botoula, Panagiotis Trivizas, Nikos C. Thalassinos Department of Endocrinology, Diabetes and Metabolism, Evangelismos Hospital, Athens, Greece Abstract Objective: Post-treatment monitoring of acromegalic patients is a matter of controversy, as discrepancies between GH and IGF-I levels have been reported. The aim of our study was to evaluate Read More

Effects of GH and IGF-I on the in vitro maturation of mouse oocytes

Erasmia Kiapekou1, Dimitris Loutradis2, Peter Drakakis2, Evangelia Zapanti1, George Mastorakos3, Aristidis Antsaklis2 11st Endocrine Section, Alexandra Hospital, Athens, Greece, 21st Department of Obstetrics and Gynaecology, Alexandra Hospital, Athens university medical school, Athens, Greece, 3Endocrine Unit, 2nd Department of Obstetrics and Gynaecology, Aretaion Hospital, Athens university medical school, Athens, Greece Abstract Objective: A number of hormones Read More