Regulation of basal metabolic rate in uncomplicated pregnancy and in gestational diabetes mellitus

Eleftheria Taousani, Dimitra Savvaki, Efrosini Tsirou, Pavlos Poulakos, Gesthimani Mintziori, Menelaos Zafrakas, Basil C. Tarlatzis, Dimitrios Vavilis, Dimitrios G. Goulis

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Basal metabolic rate (BMR) is one of the major components of total energy expenditure (TEE). It is affected by various factors, such as body weight, body composition, age, race/ethnicity, gender, biochemical parameters, physical activity, and health status. Gestational diabetes mellitus (GDM) is the most common metabolic disorder during pregnancy and it increases the risk for health complications …

Maternal serum placental growth hormone, insulin-like growth factors and their binding proteins at 20 weeks’ gestation in pregnancies complicated by gestational diabetes mellitus

Shutan Liao, Mark H. Vickers, Rennae S. Taylor, Mhoyra Fraser, Lesley M.E. McCowan, Philip N. Baker, Jo K. Perry

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OBJECTIVE: To investigate whether maternal serum concentrations of placental growth hormone (GH-V), insulin-like growth factor (IGF) 1 and 2, and IGF binding proteins (IGFBP) 1 and 3 were altered in pregnancies complicated by gestational diabetes mellitus (GDM). METHOD: In a nested case-control study, GDM cases (n=28) and matched controls (n=28) were selected from the Screening for Pregnancy Endpoints (SCOPE) biobank in Auckland, New Zealand …