Polyzois Makras, Dimitris Papadogias, Chrysoula Samara, Athanasios Zetos, Gregory Kaltsas, George Piaditis, Antony C Chu
We describe a 57-year old female with the diagnosis of skull and meningeal Langerhans’ cell histiocytosis who was treated with the combination of azathioprine and methotrexate. Although the skull lesions improved considerably on this regimen, the patient developed diabetes insipidus while the anterior pituitary function remained intact…