Nese Ozbey, Altay Sencer, Sinan Tanyolac, Ramazan Kurt, Serra Sencer, Bilge Bilgic, Inan Turantan, Senay Molvalilar
A patient with an intrasellar germinoma leading to pituitary stalk thickening is reported. The patient, a 24-year old woman, presented with hyperprolactinemia, secondary hypothyroidism, and hypogonadotropic hypogonadism with no evidence of diabetes insipidus. Cerebrospinal fluid (CSF) examination revealed an increased number of lymphocytes and histiocytes…
Polyzois Makras, Dimitris Papadogias, Chrysoula Samara, Athanasios Zetos, Gregory Kaltsas, George Piaditis, Antony C Chu
We describe a 57-year old female with the diagnosis of skull and meningeal Langerhans’ cell histiocytosis who was treated with the combination of azathioprine and methotrexate. Although the skull lesions improved considerably on this regimen, the patient developed diabetes insipidus while the anterior pituitary function remained intact…
Penelope Trimpou, Daniel S. Olsson, Olof Ehn, Oskar Ragnarsson
OBJECTIVE: Diabetes insipidus (DI) and primary polydipsia (PP) are characterised by polyuria and polydipsia. It is crucial to differentiate between these two disorders since the treatment is different. The aim of this study was to evaluate the diagnostic value of the short and an extended variant of the water deprivation test (WDT) and of measuring urinary vasopressin (AVP) in patients with polyuria and polydipsia.
DESIGN: A retrospective, single-centre study based on WDTs performed …