Disappearance of a growth hormone secreting macro adenoma during long-term somatostatin analogue administration and recurrence following somatostatin withdrawal

Sarantis Livadas, Dimitrios J. Hadjidakis, Maria I. Argyropoulou, Maria Stamatelatou, Dimitrios Kelekis, Sotirios A. Raptis

Download PDF

Acromegaly is caused by excessive growth hormone secretion, usually from a pituitary adenoma. The use of somatostatin analogues as primary or adjunctive therapy has been widely applied in the management of acromegaly. We are aware of only three reported cases of complete shrinkage of a pituitary adenoma after long-term analogue administration…