Environmental factors and nosology of the endocrine system

Catherine Dacou-Voutetakis

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The realization that the environment exerts a favorable or unfavorable effect on the human organism is not new. In the remote past, not only physicians but philosophers (e.g. Plato, Aristotle) as well wrote about the adverse effects of a maltreated environment, while Theophrastus (a student of Plato and Aristotle) is considered the father of ecology …

Polycystic Ovary Syndrome: The influence of environmental and genetic factors

Evanthia Diamanti-Kandarakis, Christina Piperi, Georgia Argyrakopoulou, Jiovanna Spina, Lambrini Papanastasiou, Angeliki Bergiele, Dimitrios Panidis

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Polycystic ovary syndrome (PCOS) is a complex and heterogeneous disorder characterized by hyperandrogenemia, hyperinsulinemia, insulin resistance, and chronic anovulation. It is the most common endocrine disorder in women of reproductive age with an enigmatic pathophysiologic and molecular basis. The high prevalence of affected …

Definition, classification and mechanism of action of endocrine disrupting chemicals

Wolfgang Wuttke, Hubertus Jarry, Dana Seidlovα-Wuttke

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Hormones are peptides/proteins, lipids or aminoacid derivatives which after their secretion act on receptors to cause reactions within the respective receptive cells. Each cell of the body is in one way or another regulated by hormones. Hence, hormones exert innumerable effects on the organism of animals and humans …

Impact of environmental endocrine disrupting chemicals on the development of obesity

Retha R. Newbold

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Environmental chemicals with hormone-like activity can disrupt programming of endocrine signaling pathways during development and result in adverse effects, some of which may not be apparent until much later in life. Recent reports link exposure to environmental endocrine disrupting chemicals during development with adverse health consequences …

Sun lotion chemicals as endocrine disruptors

Sotirios Maipas, Polyxeni Nicolopoulou-Stamati

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Ultraviolet solar radiation is a well-known environmental health risk factor and the use of sun lotions is encouraged to achieve protection mainly from skin cancer. Sun lotions are cosmetic commercial products that combine active and inactive ingredients and many of these are associated with health problems …

Environmental chemicals targeting thyroid

Thomas R. Zoeller

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Thyroid hormones (THs) are required for normal brain and somatic development and for the proper regulation of physiology in both children and adults. Thyroid function is controlled by the dynamic interrelationships between the hypothalamus, the pituitary and the thyroid. These dynamic relationships maintain circulating levels of THs …