Polyzois Makras, Georgios Toloumis, Dimitrios Papadogias, Gregory A. Kaltsas, Michael Besser
Cushing’s syndrome (CS) is a physically and psychologically disabling disease associated with high morbidity resulting from inappropriate elevation of circulating free cortisol levels. The main features of CS are disturbance of the normal circadian rhythm of cortisol secretion, impairment of the normal feedback of the hypothalamo-pituitary-adrenal (HPA)-axis …