Polyzois Makras, Dimitris Papadogias, Chrysoula Samara, Athanasios Zetos, Gregory Kaltsas, George Piaditis, Antony C Chu
We describe a 57-year old female with the diagnosis of skull and meningeal Langerhans’ cell histiocytosis who was treated with the combination of azathioprine and methotrexate. Although the skull lesions improved considerably on this regimen, the patient developed diabetes insipidus while the anterior pituitary function remained intact…
Pinelopi Katsiveli, Maria Sfakiotaki, Nikolaos Voulgaris, Labrini Papanastasiou, Theodora Kounadi, Konstantinos Lymperopoulos, George Piaditis
Primary hypophysitis (PH) is a rare clinical entity characterized by inflammatory infiltration of the pituitary gland with various degrees of pituitary dysfunction. OBJECTIVE: To present a complicated case of aggressive PH with bilateral cavernous sinuses infiltration, successfully treated with azathioprine after failure of corticosteroid treatment. METHODS AND RESULTS: A 48-year-old woman presented with episodes of recurrent headache …