Hormones in pain modulation and their clinical implications for pain control: a critical review

Xueyin Chen, Jinyuan Zhang, Xiangrui Wang

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Recently, more and more studies have found that pain generation, transmission and modulation are under hormonal regulation. Indeed, hormonal dysregulation is a common component of chronic pain syndromes. Studies have attempted to determine whether the relationship between the pain and its perception and hormones is a causative relationship and how these processes interrelate …