Compensatory adrenal growth in relation to stress of surgery and estradiol in adult male rats

Nicholas Bikas, Joan Gribisi, Joan Messari and Anastasia Sfikakis

ACTH infusion at the time of unilateral adrenalectomy inhibits the early rapid compensatory growth (CAG) in the remaining adrenal. We examined the hypothesis that different duration of surgery and/or the enhanced response to the stress of surgery, induced by estradiol treatment, might modify CAG. Adult male rats untreated …