Androgen receptors in early and castration resistant prostate cancer: friend or foe?

Vassiliki Pelekanou, George Notas, Efstathios N. Stathopoulos, Elias Castanas, Marilena Kampa

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Prostate cancer is one of the most common malignancies and causes of death among men in western societies. It has thus attracted the interest of the scientific community, which has resulted in great improvements in survival rates in recent years. As early as the 1940s, Huggins and Hodges first demonstrated that prostate cancer is androgen dependent …