Eirini Lioudaki, Niki G. Mavroeidi, Dimitri P. Mikhailidis, Emmanouel S. Ganotakis
Subclinical hypothyroidism (SCH), defined as elevated serum thyroid-stimulating hormone (TSH) in the presence of normal circulating free thyroxine (FT4) and triiodothyronine (T3), is a relatively common condition. Replacement treatment with levothyroxine is justified only for individuals with TSH levels >10 mIU/l …
Leonidas H. Duntas, Gabriela Brenta
L-thyroxine (LT4) treatment of hypothyroidism, particularly in patients with thyroid- stimulating hormone (TSH) >10mU/L, results in improved lipid profile, as LT4 stimulates low-density lipoprotein cholesterol (LDL-C) degradation and the conversion of cholesterol in bile acids by inducing LDL-receptor and 7 alpha hydroxylase expression …
Genovefa D. Kolovou, Vana Kolovou, Demosthenes B. Panagiotakos, Ioannis Vasiliadis, Vassiliki Giannakopoulou, Peggy M. Kostakou, Vassiliki Vartela, Sophie Mavrogeni
OBJECTIVE: In the present study, we evaluated the influence of lipoprotein lipase (LPL) and apolipoprotein (apo) E polymorphisms on lipid concentrations of 178 Greek men of similar age with coronary heart disease (CHD), but varying body mass index (BMI). DESIGN: Patients were divided according to their BMI …
Odysseas Gregoriou,George Christodoulakos, Charalambos Siristatidis, Socrates Conidaris, Evangelia Kouskouni, George Creatsas
Objective: The purpose of this study was to examine the effects of Hormone Replacement Therapy (HRT) on plasma lipoprotein levels, bone mass and the endometrium. Methods: Thirty healthy women were enrolled in the study for climacteric symptoms and received a combination of 17β-estradiol and norethisterone acetate continuously for 2 years …