Growth hormone therapy – HORMONES (Archive)

Changes in prothrombin and activated partial thromboplastin time during replacement therapy with human recombinant growth hormone in growth hormone deficient adults

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Dragana Miljic, Predrag Miljic, Mirjana Doknic, Sandra Pekic, Marina Djurovic, Milica Colovic, Vera Popovic

BACKGROUND: In rodents, Growth Hormone (GH) has been shown to stimulate coagulation parameters, including Prothrombin Time (PT), activated Partial Thromboplastin Time (aPTT) and vitamin K dependent coagulation factors. However, there are no reports on the influence of GH replacement therapy on global coagulation tests in Growth Hormone Deficiency (GHD)…

Long-term follow-up results of growth hormone therapy for patients with adult growth hormone deficiency

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Hidetoshi Ikeda, Masataka Kudo

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Objective: We evaluated the long-term effects of growth hormone (GH) on markers of quality of life, glucose metabolism, and lipid metabolism to validate the adequacy of long-term GH replacement therapy for adult GH deficiency (AGHD). Design: Eighty-three of 100 sequentially followed patients who received GH therapy …