The use of bisphosphonates in women prior to or during pregnancy and lactation

Stathopoulos P. Ioannis, Liakou G. Chrysoula, Katsalira Aikaterini, Trovas George, Lyritis P. George, Papaioannou A. Nikolaos, Tournis Symeon

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OBJECTIVE: The unique pharmacokinetics of bisphosphonates (BPs) in conjunction with their use by an increasing number of women at reproductive age has raised serious concerns about their safety during pregnancy and lactation. Bisphosphonates cross the placenta. Animal studies have shown adverse effects on both the fetus and the mother …

Case Report: Teriparatide treatment in a case of severe pregnancy -and lactation- associated osteoporosis

Kalliopi Lampropoulou-Adamidou, George Trovas, Ioannis P. Stathopoulos, Nikolaos A. Papaioannou

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OBJECTIVE: Pregnancy- and lactation-associated osteoporosis (PLO) is an uncommon disease. The majority of cases are seen in the third trimester or early post-partum in primagravid women and the prominent clinical feature of PLO is severe and prolonged back pain and height loss. The prevalence and aetiology of this disorder …