Differentiated thyroid cancer in children and adults: same or distinct disease?

Barbara Jarzab, Daria Handkiewicz-Junak

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Differentiated thyroid cancer (Dtc) is a rare disease, especially in children. Differences in the biology and clinical course of Dtc in children, when compared with adults, may be related both to pathogenesis as well as to clinical outcome of the disease. In childhood, the thyroid gland exhibits higher susceptibility to the carcinogenetic …

Differentiated thyroid cancer in childhood: a literature update

Olga Karapanou, Marinella Tzanela, Barbara Vlassopoulou, Christina Kanaka-Gantenbein

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Differentiated thyroid cancer in childhood is rare. Apart from family history, radiation exposure is a major risk factor. Although its clinical course is quite aggressive with higher rates of lymph node and pulmonary metastases as compared to adults, the final outcome tends to be favorable with mortality rates less than 2% …