A case of idiopathic granulomatous hypophysitis

Nilufer Ozdemir Kutbay, Mustafa Berker, Figen Soylemezoglu, Hatice Ozisik, Banu Sarer Yurekli

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Dear Sir, Hypophysitis is a rare disease of the pituitary gland whose incidence is 1 case per 9 million people per year. Hypophysitis, which can be categorized as primary (idiopathic) hypophysitis and secondary hypophysitis, may develop through systemic inflammatory disorders such as tuberculosis, Wegener’s granulomatosis and sarcoidosis. Based on histologic features …

Landmarks in the history of adrenal surgery

Marios Papadakis, Andreas Manios, Georgios Schoretsanitis, Constantinos Trompoukis

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The last 100 years have seen a revolution in the understanding of adrenal disease and its surgical treatment. The isolation of its hormones, the detailed study of the adrenal medulla and the cortex together with the enormous expansion of surgical methods served as catalysts to this revolution. The Greek word for adrenal (epinephridio, from the Greek epi, upon, and nephros, kidney) dates back to the age of Homer who mentions the adrenal glands …

Congenital nephrogenic diabetes insipidus in the Corpus Hippocraticum: The first description

Gregory Tsoucalas, Marianna Karamanou

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Dear Editor, In congenital nephrogenic diabetes insipidus (cNDI), polyuria and polydipsia are present from birth, as the kidney is unable to concentrate urine despite elevated concentrations of the antidiuretic hormone arginine-vasopressin. In ancient Greek medicine, physiology was, needless, to say, an as yet fairly undeveloped specialty among medico-philosophers …

Menophila: a poetic description of genital ambiguity in Hellenistic literature

Anastasia K. Armeni, Danai Georgakopoulou, Georgios K. Markantes, Konstantina Barouti, Leonidas Liarakos, Vasiliki Vasileiou, Neoklis A. Georgopoulos

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In Ancient Greece, up to the Classical era, hermaphrodites were regarded as “monstrous” beings, messengers of evil or a sign of divine anger. They were consequently socially marginalized, being treated cruelly or even put to death …

Does ambient light at night reduce total melatonin production?

Christopher C.M. Kyba, Thomas Kantermann

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It was with great interest that we read the recent study by Hersh et al. on the effects of sleep and light at night on melatonin in adolescents. Of particular interest was their focus on electronic use after “lights out”. The authors highlight the importance of understanding what effects this may have on sleep, citing a survey that showed that 72% of American 13-18 year olds regularly use a cellphone or computer before trying to go to sleep …

Central precocious puberty due to hypothalamic hamartoma in neurofibromatosis type 1

Emanuele Bartolini, Stefano Stagi, Perla Scalini, Andrea Bianchi, Antonio Ciccarone, Mario Mascalchi

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In neurofibromatosis type 1 (NF1), Central Precocious Puberty (CPP) occurs almost invariably in association with optic pathway tumors, usually pilocytic astrocytoma. However, at times the aetiology remains. On the other hand, in the general population CPP develops due to an underlying hypothalamic hamartoma in up to 10% of patients. To the best of our knowledge, CPP due to hypothalamic hamartomas in NF1 has been reported only once in the literature …

Melampus and the cure of Proetus’ daughters

Vasiliki Vasileiou, Georgios K. Markantes, Anastasia K. Armeni, Konstantina Barouti, Angeliki Georgopoulou, Neoklis A. Georgopoulos

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Dear Editor, In Greek mythology, Melampus, son of Amythaon was a seer and healer. His name means “black foot” or “man with the black feet” as, according to the legend, when he was a neonate he was left by his mother with his feet exposed to the bright sun. Being the Greek prototype of the shaman, he was, according to Herodotus, the introducer of the worship of Dionysus and the creator of an entire school of magic …

Diversity in endocrinology practice: the case of Ramadan

Ioannis Ilias, Luai Said Tayeh, Isidoros Pachoundakis

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There is today an imperative need to raise health workers’ awareness of contemporary cultural diversity and different beliefs, values and attitudes concerning health and disease in order to provide culturally appropriate and professionally competent care. Muslims currently account for 1%-10% of the population in Western Europe …