Growth and growth hormone secretion in paediatric Cushing’s disease

Martin O. Savage, Helen L. Storr, Ashley B. Grossman, Gerasimos E. Krassas

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Although paediatric Cushing’s disease is rare, it is associated with severe morbidity in childhood and presents a major diagnostic and therapeutic challenge for the paediatric endocrinologist. Growth failure remains an important feature of paediatric Cushing’s disease, both at diagnosis and after successful treatment. However, the development of specific diagnostic tests and important therapeutic advances has contributed …