The pluses and minuses of bariatric surgery for morbid obesity: An endocrinological perspective

Antonis Polymeris

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Obesity both in adults and children has emerged as a worldwide epidemic. Obesity is associated with an increased risk of a number of comorbidities including type 2 diabetes mellitus, hypertension, dyslipidemia, obstructive sleep apnea …

Serum and glucocorticoid inducible kinase, metabolic syndrome, inflammation, and tumor growth

Florian Lang, Christos Stournaras

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Serum-and-glucocorticoid-inducible-kinase-1 (SGK1) is under regulation of several hormones, mediators and cell stressors. More specifically, SGK1 expression is particularly sensitive to glucocorticoids, mineralocorticoids, and TGFβ. Moreover, SGK1 expression is exquisitely sensitive to hypertonicity, hyperglycemia, and ischemia …

A 50-year follow-up of the Seven Countries Study: Prevalence of cardiovascular risk factors, food and nutrient intakes among Cretans

Christos M. Hatzis, Christopher Papandreou, Evridiki Patelarou, Constantine I. Vardavas, Eleni Kimioni, Dimitra Sifaki-Pistolla, Anna Vergetaki, Anthony G. Kafatos

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OBJECTIVE: To identify the cardiovascular disease (CVD) risk-factor status and dietary habits of the surviving elderly participants of the initial Seven Countries Study (SCS) cohort and newly recruited middle-aged men from the same villages …

Phaeochromocytoma crisis presenting with profound hypoglycaemia and subsequent hypertension

Sarah Frankton, Suhail Baithun, Ehab Husain, Katherine Davis, Ashley B. Grossman

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A patient was presented with four days of vomiting, abdominal pain and sweating. At presentation the Capillary Blood Glucose (CBG) was 1.7 mmol/L, the Blood Pressure (BP) was 182/102 mmHg, and the pulse 100 bpm. On examination, he was sweaty, pale and cold. The initial differential diagnosis was hypoglycaemia secondary to insulin abuse, hypoadrenalism or insulinoma …