The impact of thyroid autoimmunity (TPOAb) on bone density and fracture risk in postmenopausal women

Snezana P. Polovina, Dragana Miljic, Sladjana Zivojinovic, Natasa Milic, Dragan Micic, Vera Popovic Brkic

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OBJECTIVE: Skeletal development, linear growth, cartilage biology and bone turnover are highly dependent on the activity of thyroid hormones. Thyroid dysfunction affects the skeleton, and autoimmune thyroid disease, manifesting as a chronic inflammatory condition, may be an important contributing factor to impaired bone quality in these patients. MATERIALS AND METHODS: Measurement of TSH, FT4, TPOAb and bone mineral density and FRAX score calculations were performed …

Use of the FRAX calculator with and without bone mineral density in Greek women

Ioannis Ilias, Filio Spanoudi, Eftychia Koukkou, Stamatina C. Nikopoulou

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The creators of the FRAX fracture risk calculator for countries with no national reference values (such as Greece) suggest the use of FRAX from a neighboring country. For Greeks (considered to run a high risk for osteoporotic fractures) …