Muscular effects of vitamin D in young athletes and non-athletes and in the elderly

Nikolaos E. Koundourakis, Pavlina D. Avgoustinaki, Niki Malliaraki, Andrew N. Margioris

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Muscles are major targets of vitamin D. Exposure of skeletal muscles to vitamin D induces the expression of multiple myogenic transcription factors enhancing muscle cell proliferation and differentiation. At the same time vitamin D suppresses the expression of myostatin, a negative regulator of muscle mass …

Sarcopenia: From definition to treatment

Yannis Dionyssiotis, Athina Kapsokoulou, Eleni Samlidi, Antonios G. Angoules, Jannis Papathanasiou, Efstathios Chronopoulos, Ifigenia Kostoglou-Athanassiou, Georgios Trovas

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Over the last few decades, worldwide average life expectancy has grown significantly and therefore the percentage of the elderly has correspondingly increased. As a result, clinical medicine has focused much interest on the latter age group and their health problems. During the 20th century, the typical elderly patient was a person with an acute or chronic disease …