Transient Congenital Hypothyroidism due to maternal autoimmune thyroid disease

Chryssanthi Mengreli, Maria Maniati-Christidi, Christina Kanaka-Gantenbein, Panagiotis Girginoudis, Apostolos G. Vagenakis, Catherine Dacou-Voutetakis

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The neonatal screening program for congenital hypothyroidism (CH) in Greece shows an overall incidence of the disease of 1:2321. The cases with permanent CH have an incidence of 1:2542, whereas the transient forms of CH account for 8.7% of all cases diagnosed as CH. Transplacental passage of maternal thyrotropin receptor-blocking antibodies is a rare cause of transient CH …