Macroprolactinemia. Is treatment necessary?

Irene V. Lambrinoudaki, Olga D. Daskalaki, Stathis A. Thomopoulos, Panayiotis Schinochoritis, Argyris B. Argyropoulos

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A 26-year old symptom-free woman was admitted to our Clinic for evaluation of hyperprolactinemia. The patient, who had normal menstrual cycles, was found accidentally to have a cystic adnexal mass and was placed on oral contraceptives (OC) for 3 months. During the first OC-cycle a bilateral breast nipple discharge was noticed and an elevated serum prolactin (PRL) was detected (2.7 nmol/l) …

Macroprolactinemia in a young man and review of the literature

Evangeline Vassilatou, Panayiotis Schinochoritis, Stamatina Marioli, Ioanna Tzavara

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A 21-year old man, complaining of headaches and fatigue, with a negative past medical history and a normal clinical examination, underwent a hormonal investigation which revealed hyper-prolactinemia and intact pituitary-gonadal axis. Drug-induced hyperprolactinemia was excluded …