The role of iodine and δ-iodolactone in growth and apoptosis of malignant thyroid epithelial cells and breast cancer cells

Roland Gärtner, Petra Rank, Birgit Ander

Download PDF

OBJECTIVE: As we previously demonstrated, the inhibitory effect of iodine on thyroid cell growth is mediated by iodolactones, especially 6-iodo-5-hydroxy-eicosatrienoic acid (δ-iodolactone). In this communication we compare the effect of iodide, molecular iodine and δ-iodolactone on growth inhibition and apoptosis on three human thyroid carcinoma cell lines …