Tag: CRF-receptors
Corticotropin-releasing factor (CRF) system localization in human fetal heart
Efterpi Chouridou, Maria Lambropoulou, Maria Koureta, Christina Zarouchlioti, Ioanna Balgouranidou, Evangelia Nena, Nikolaos Papadopoulos, Ekaterini Chatzaki
OBJECTIVE: The corticotropin-releasing factor (CRF) family consists of the neuropeptides CRF, Ucn I, II and III and the binding sites CRFR1, CRFR2 and CRF-BP. It regulates stress response and the homeostasis of an organism. In this study, we examined the presence of the CRF system in the human hearts of normal and pathological fetuses. DESIGN: Heart tissues from 40 archival human fetuses were divided …