Isolated adrenocorticotropin deficiency and flexion contractures syndrome

Vassiliki Syriou, Anestis Moisidis, Nikolaos Tamouridis, Krystallenia I. Alexandraki, Margarita Anapliotou

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We present a 73-year-old man with isolated adrenocorticotropic hormone deficiency and “flexion contractures” syndrome along with a review of the relevant literature. The patient initially presented anorexia, vomiting, arthralgias, malaise, and weight loss, which progressively deteriorated during the subsequent 6 months. He was admitted to the hospital with fever, confusion, severe cachexia, sinus tachycardia, low blood pressure …