Bone disease in anorexia nervosa

Anastasia D. Dede, George P. Lyritis, Symeon Tournis

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Anorexia nervosa is a serious psychiatric disorder accompanied by high morbidity and mortality. It is characterized by emaciation due to self-starvation and displays a unique hormonal profile. Alterations in gonadal axis, growth hormone resistance with low insulin-like growth factor I levels, hypercortisolemia and low triiodothyronine …

Serum kisspeptin concentrations are negatively correlated with body mass index in adolescents with anorexia nervosa and amenorrhea

Flora Bacopoulou, George I. Lambrou, Maria-Evangelia Rodanaki,Evgenia Stergioti, Vasiliki Efthymiou, Efthymios Deligeoroglou, Sophia L. Markantonis

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OBJECTIVE: To measure, for the first time, serum kisspeptin concentrations in adolescent females with anorexia nervosa (AN) and associated amenorrhea, and investigate potential correlations of kisspeptin with anthropometric, bone and hormonal data. DESIGN: Setting: University Adolescent Medicine Center. Participants: Females aged 12-20 years with typical or atypical AN (based on DSM-5 diagnostic criteria) and controls …