Severe water intoxication secondary to the concomitant intake of non-steroidal anti-inflammatory drugs and desmopressin: a case report and review of the literature

Elisa Verrua, Giovanna Mantovani, Emanuele Ferrante, Andrea Noto, Elisa Sala, Elena Malchiodi, Gaetano Iapichino, Paolo Beck-Peccoz, Anna Spada

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Most of the clinical data on the safety profile of desmopressin (DDAVP), which is an effective treatment for both polyuric conditions and bleeding disorders, originate from studies on the tailoring of drug treatment, whereas few reports exist describing severe side effects secondary to drug-drug interaction …