Cardiovascular safety of type 2 diabetes medications: Review of existing literature and clinical implications

Sílvia Paredes, Claudia Matta-Coelho, Ana Margarida Monteiro, Alice Brás, Olinda Marques, Marta Alves, Laura Ribeiro

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Type 2 diabetes mellitus (T2DM), cardiovascular disease (CVD) and the cardiovascular effect of antidiabetic drugs are today critical medical issues, with the prevalence of T2DM in particular showing a steep increase worldwide, mainly due to unhealthy lifestyle habits. T2DM in association with obesity and other cardiovascular risk factors, results in the development of CVD, the leading cause of morbidity and mortality in patients with T2DM …