Anna Angelousi, Filip Fencl, Fabio R. Faucz, Jana Malikova, Zdenek Sumnik, Jan Lebl, Constantine A. Stratakis
OBJECTIVE: Corticotropin (ACTH)-independent hypercortisolism due to bilateral adrenocortical hyperplasia (BAH) in infancy is an extremely rare condition that is often caused by McCune Albright syndrome (MAS). MAS is caused by an activating mutation of the GNAS gene which leads to increased cyclic (c) adenosine monophosphate (AMP) signaling …