Effect of weight loss with or without orlistat treatment on adipocytokines, inflammation, and oxidative markers in obese women

Maria Bougoulia, Athanassios Triantos, George Koliakos

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OBJECT IVE: T he aim of this study was to evaluate the levels of adipose tissue related hormones, cytokines, and antioxidative substances in obese women before and after intervention with diet alone or with diet plus an inhibitor of gastrointestinental lipase-orlistat…

Early onset adiposity: A pathway to polycystic ovary syndrome in adolescents?

Evanthia Diamanti-Kandarakis, Charikleia D. Christakou, Eleni Kandaraki, Krystallenia I. Alexandraki

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Polycystic Ovary Syndrome is a heterogenous syndrome of unknown causation commonly associated with obesity. Τhe particular timing of the onset of obesity may be important, since the earlier the onset of obesity the greater the severity of the metabolic and hormonal aberrations …

Ghrelin and leptin levels in obese adolescents. Relationship with body fat and insulin resistance

Charilaos Stylianou, Assimina Galli-Tsinopoulou, Dimitrios Farmakiotis, Israel Rousso, Michael Karamouzis, George Koliakos, Sanda Nousia-Arvanitakis

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OBJECTIVE: Ghrelin and leptin levels are influenced by body fat (BF%), pubertal stage and possibly insulin resistance (IR). The aim of our study was: 1) To compare fasting ghrelin and leptin levels between obese and non-obese, adolescents, 2) to investigate possible correlations of these hormones with BF %, as well as IR…