Efstathia Papageorgiou, Anastassios Philippou, Athanasios Armakolas, Panagiotis F. Christopoulos, Andreas Dimakakos, Michael Koutsilieris
OBJECTIVE: Preferential IGF-1Ec expression has been firmly associated with skeletal muscle repair mechanisms, post-infarction remodeling of the myocardium, the pathophysiology of endometriosis and prostate cancer biology. Therefore, we have studied the possible biological significance of synthetic Ec peptide, a putative cleavage product of IGF-1Ec in PC-3 cells and C2C12 myoblasts …