Papillary thyroid carcinoma producing granulocyte-macrophage colony-stimulating factor is associated with neutrophilia and eosinophilia

Evangeline Vassilatou, Markos Fisfis, George Morphopoulos, Sotiria Savva, Eugenia Voucouti, Katerine Stefanoudaki, Ioanna Tzavara

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Thyroid tumors producing colony-stimulating factors associated with neutrophilia and/or eosinophilia are very rare and almost all of them concern anaplastic thyroid cancer. Only one case of papillary thyroid carcinoma associated with neutrophilia and one case of medullary thyroid carcinoma associated with eosinophilia have been reported.

Role of color Doppler ultrasonography in the preoperative management of cold thyroid nodules

Emmanuel Varverakis, Evaggelos Neonakis, Maria Tzardi, Emmanuel Chrysos

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OBJECTIVE: To evaluate the application of color flow Doppler (CFD) sonography in the preoperative management of benign and malignant cold thyroid nodules. DESIGN: Eighty-five patients with a cold thyroid nodule larger than 1cm were examined with CFD sonography prior to thyroidectomy. The histological examination revealed that 18 (21%) patients had malignant nodules …

Thyroid cancer in childhood: Management strategy, including dosimetry and long-term results

Markus Luster, Michael Lassmann, Lutz S. Freudenberg, Christoph Reiners

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Thyroid cancer, although very rare in childhood, represents the most common pediatric endocrine neoplasia. The low incidence and the resulting limited availability of prospective, randomized trials lead to a lack of evidence- based recommendations for treatment strategies. Total thyroidectomy and lymphadenectomy …

Which is the best predictor of thyroid cancer: thyrotropin, thyroglobulin or their ratio?

Pinar Yazici, Mehmet Mihmanli, Emre Bozkurt, Feyza Yener Ozturk, Mehmet Uludag

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OBJECTIVE: Since documented incidence of thyroid cancer has been rising over time, in part due to incidental small papillary cancer, several studies have been carried out to investigate the role of possible serum markers of thyroid cancer prior to surgery. DESIGN: Prospective cohort study. AIM: To investigate the role of thyroglobulin (Tg), thyrotropin (TSH) and the TSH:Tg, Tg:TSH ratio in the preoperative diagnosis of thyroid cancer …