Serkan Yener,1 Abdurrahman Comlekci,1 Baris Akinci,1 Pinar Akan,2 Tevfik Demir,1 Firat Bayraktar,1 Sena Yesil1 1Dokuz Eylul University, Department of Internal Medicine, Division of Endocrinology and Metabolism, 2Dokuz Eylul University, Department of Biochemistry, Izmir, Turkey Abstract OBJECTIVE: a)To determine serum Transforming Growth Factor-beta 1 (TGF-β1) levels in patients with type 2 diabetes who do not have Read More
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A female infant with Silver Russell Syndrome, mesocardia and enlargement of the clitoris
Assimina Galli-Tsinopoulou,1 Eleftheria Emmanouilidou,1 Paraskevi Karagianni,2 Maria Grigoriadou,3 John Kirkos,4 George S. Varlamis1 14th Department of Pediatrics, 22nd Neonatal Intensive Care Unit and Neonatology Department, Medical School, Aristotle University of Thessaloniki, 3Department of Genetics, Institute of Child Health, Athens, 43rd Orthopaedic Department, Medical School, Aristotle University of Thessaloniki, Greece Abstract Silver Russell Syndrome (SRS) is Read More
The length of life and eugeria in classical Greece
Menelaos L. Batrinos Emeritus Professor of Endocrinology Abstract Contrary to the commonly held belief that in antiquity and as late as 1700 A.D. normal lifespan was about 35 years, there are indications that the ancient Greeks lived longer. In a study of all men of renown, living in the 5th and 4th century in Greece, Read More
Early-life events. Effects on aging
Eero Kajantie National Public Health Institute, Helsinki, Finland Abstract During the last two decades, a considerable body of evidence has emerged showing that circumstances during the fetal period and childhood may have lifelong programming effects on different body functions with a considerable impact on disease susceptibility. From a medical point of view, these long-term effects Read More
Oxidative stress and aging: the potential role of iron
Dimitrios Galaris, Michalis Mantzaris, Christos Amorgianiotis Laboratory of Biological Chemistry, University of Ioannina Medical School, Ioannina, Greece Abstract According to the free radical theory of aging proposed by Denham Harman more than 50 years ago, oxidatively modified cellular components accumulate continuously in the cells during the organism’s lifespan leading to progressive decline of cellular functions. Read More
Aging and glycoxidant stress
Melpomeni Peppa,1 Jaime Uribarri,2 Helen Vlassara3 1Endocrine Unit, 2nd Dept of Internal Medicine-Propaedeutic, Research Institute and Diabetes Center, Athens University, Medical School, Athens, Greece, 2Division of Nephrology, Dept of Medicine and 3Experimental Diabetes and Aging, Dept of Geriatrics, Mount Sinai School of Medicine, NY, USA Abstract Aging and related diseases are accompanied by increased Oxidative Read More
Growth hormone treatment in human ageing: benefits and risks
Roberta Giordano, Lorenza Bonelli, Elisa Marinazzo, Ezio Ghigo, Emanuela Arvat Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Turin, Turin, Italy Abstract This paper will focus on the rationale of using Growth Hormone (GH) as an anti-ageing therapy in the healthy elderly with age-related decline in the activity of the GH/IGF-I axis, Read More
Serum inhibin-B and follicle stimulating hormone as predictors of the presence of sperm in testicular fine needle aspirate in men with azoospermia
Dimitrios G. Goulis, Paris Polychronou, Themistokis Mikos, Grigorios Grimbizis, Sriridon Gerou, Vassiliki Pavlidou, Athanasios Papanikolaou, Basil C. Tarlatzis, Ioannis N. Bontis, Ioannis Papadimas Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Thessaloniki, Greece Abstract Objective: Inhibin-B (Inh-B) is produced by Sertoli cells and controls Follicle Stimulating Hormone (FSH) secretion Read More
Severity of coronary artery disease in postmenopausal diabetic women
Katerina Saltiki,1 Adrianna Cimponeriu,1 Kyriaki Lili,1 Melpomeni Peppa,2 Eleni Anastasiou,3 Maria Alevizaki1 1Endocrine Unit, Evgenidion Hospital and Department of Clinical Therapeutics, Alexandra University Hospital, 22nd Department of Internal Medicine, Research Unit & Diabetes Centre, Attikon University Hospital, 31st Endocrine Section & Diabetes Centre, Alexandra University Hospital, Athens, Greece Abstract Objective: Coronary artery disease (CAD) risk Read More
Evaluation of markers of inflammation, insulin resistance and endothelial dysfunction in children at risk for overweight
Gulcin Akinci1, Baris Akinci2, Senol Coskun3, Petek Bayindir4, Zeliha Hekimsoy5, Bilgin Ozmen5 1Department of Pediatrics, Celal Bayar University Medical School, Manisa, 2Division of Endocrinology and Metabolism, Department of Internal Medicine, Dokuz Eylul University Medical School, Izmir, 3Division of Pediatric Cardiology, Department of Pediatrics, Celal Bayar University Medical School, 4Department of Radiology, Celal Bayar University Medical Read More