Dimitrios Galaris, Michalis Mantzaris, Christos Amorgianiotis Laboratory of Biological Chemistry, University of Ioannina Medical School, Ioannina, Greece Abstract According to the free radical theory of aging proposed by Denham Harman more than 50 years ago, oxidatively modified cellular components accumulate continuously in the cells during the organism’s lifespan leading to progressive decline of cellular functions. Read More
Author: admin
Aging and glycoxidant stress
Melpomeni Peppa,1 Jaime Uribarri,2 Helen Vlassara3 1Endocrine Unit, 2nd Dept of Internal Medicine-Propaedeutic, Research Institute and Diabetes Center, Athens University, Medical School, Athens, Greece, 2Division of Nephrology, Dept of Medicine and 3Experimental Diabetes and Aging, Dept of Geriatrics, Mount Sinai School of Medicine, NY, USA Abstract Aging and related diseases are accompanied by increased Oxidative Read More
Growth hormone treatment in human ageing: benefits and risks
Roberta Giordano, Lorenza Bonelli, Elisa Marinazzo, Ezio Ghigo, Emanuela Arvat Division of Endocrinology and Metabolism, Department of Internal Medicine, University of Turin, Turin, Italy Abstract This paper will focus on the rationale of using Growth Hormone (GH) as an anti-ageing therapy in the healthy elderly with age-related decline in the activity of the GH/IGF-I axis, Read More
Serum inhibin-B and follicle stimulating hormone as predictors of the presence of sperm in testicular fine needle aspirate in men with azoospermia
Dimitrios G. Goulis, Paris Polychronou, Themistokis Mikos, Grigorios Grimbizis, Sriridon Gerou, Vassiliki Pavlidou, Athanasios Papanikolaou, Basil C. Tarlatzis, Ioannis N. Bontis, Ioannis Papadimas Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, Aristotle University of Thessaloniki, Thessaloniki, Greece Abstract Objective: Inhibin-B (Inh-B) is produced by Sertoli cells and controls Follicle Stimulating Hormone (FSH) secretion Read More
Severity of coronary artery disease in postmenopausal diabetic women
Katerina Saltiki,1 Adrianna Cimponeriu,1 Kyriaki Lili,1 Melpomeni Peppa,2 Eleni Anastasiou,3 Maria Alevizaki1 1Endocrine Unit, Evgenidion Hospital and Department of Clinical Therapeutics, Alexandra University Hospital, 22nd Department of Internal Medicine, Research Unit & Diabetes Centre, Attikon University Hospital, 31st Endocrine Section & Diabetes Centre, Alexandra University Hospital, Athens, Greece Abstract Objective: Coronary artery disease (CAD) risk Read More
Evaluation of markers of inflammation, insulin resistance and endothelial dysfunction in children at risk for overweight
Gulcin Akinci1, Baris Akinci2, Senol Coskun3, Petek Bayindir4, Zeliha Hekimsoy5, Bilgin Ozmen5 1Department of Pediatrics, Celal Bayar University Medical School, Manisa, 2Division of Endocrinology and Metabolism, Department of Internal Medicine, Dokuz Eylul University Medical School, Izmir, 3Division of Pediatric Cardiology, Department of Pediatrics, Celal Bayar University Medical School, 4Department of Radiology, Celal Bayar University Medical Read More
The Republic of Srpska Iodine Deficiency Survey 2006
Amela Lolic,1 Νenad Prodanovic2 1Ministry of Health and Social Welfare, 2Military Medical Academy, the Republic of Srpska Abstract Objective: A survey related to iodine deficiency in the Republic of Srpska was first conducted in 1999 and resulted in the adoption of regulations concerning the quality of salt for human consumption. In order to reassess iodine Read More
Precocious pseudopuberty due to autonomous ovarian cysts: A report of ten cases and long-term follow-up
Gideon de Sousa, Rainer Wunsch, Werner Andler Vestische Kinder, Jugendklinik Datteln, University of Witten/Herdecke, Datteln, Germany Abstract We report the findings and clinical course of ten girls aged 0.2 to 6.3 years with precocious pseudopuberty due to autonomous ovarian cysts. We found elevated oestrogen levels in five patients and failure of gonadotropin response to GnRH Read More
Autonomously functioning thyroid nodule treated with radioactive iodine and later diagnosed as papillary thyroid cancer
Mehmet Uludag,1 Gurkan Yetkin,1 Bulent Citgez,1 Adnan Isgor,2 Tulay Basak3 1Department of 2nd General Surgery, Sisli Etfal Training and Research Hospital, Sisli, 2Golden Horn University, Aksaray, 3Department of Pathology, Sisli Etfal Training and Research Hospital, Sisli, Istanbul, Turkey Abstract The malignancy risk is low in hot thyroid nodules verified by scintigraphy. We present a rare Read More
Rosiglitazone-induced anasarca without heart failure: capillary leakage?
Selcuk Dagdelen,1 Mevlut Kurt,2 Kadriye Aydιn,2 Miyase Bayraktar1 1Hacettepe University School of Medicine, Departments of Endocrinology and Metabolism, 2Internal Medicine, Ankara, Turkey Abstract Severity of thiazolidinedione (Rosiglitazone)-induced fluid retention is linked almost exclusively to cardiac decompensation. We here report a 68-year old female with type 2 diabetes mellitus, in whom a life-threatening (anasarca type) acute Read More