Aristidis Diamantis1, George Androutsos2 1Department of Cytopathology, Naval Hospital of Athens, Athens, 2Department of History of Medicine, Ioannina University School of Medicine, Ioannina, Greece Abstract In 1847 Felix-Archimede Pouchet effectively launched the study of the physiology of cytology. Now 160 years later, the authors briefly trace the development of hormonal cytology to our present knowledge Read More
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The liaison of the young endocrine patient with the adult endocrinologist. On the occasion of a prismatic case
Editorial The case presented by Petzold et al in this issue1 highlights certain critical aspects of management of the child and adolescent with endocrine problems which are both of theoretical and practical interest. First, the discrepancy between the hormonal profile and the clinical manifestations, as described in this case, although not novel are, nevertheless, Read More
Ectopic Cushing?s syndrome due to CRH secreting liver metastasis in a patient with medullary thyroid carcinoma
Alexandra Chrisoulidou1, Kalliopi Pazaitou-Panayiotou1, Eleni Georgiou1, Maria Boudina1, George Kontogeorgos2, Ioannis Iakovou1, Ioannis Efstratiou3, Frideriki Patakiouta4, Iraklis Vainas1 1Unit of Endocrinology & Endocrine Oncology, “Theagenio” Cancer Hospital, Thessaloniki, 2Unit of Pathology, “G. Gennimatas” Athens General Hospital, 3Unit of Pathology, “Papageorgiou” Hospital, 4Unit of Pathology, “Theagenio” Cancer Hospital, Thessaloniki, Greece Abstract Ectopic production of CRH by Read More
Hypothalamic-pituitary-adrenal axis in patients with ankylosing spondylitis
Mehmet Kirnap1, Hulusi Atmaca2, Fatih Tanriverdi2, Osman Ozsoy1, Kursad Unluhizarci2, Fahrettin Kelestimur2 1Department of Physical Medicine and Rehabilitation, 2Department of Endocrinology and Metabolism, Erciyes University Medical School, Kayseri, Turkey Abstract OBJECTIVE: To investigate the hypothalamic-pituitary-adrenal (HPA) axis via the insulin-tolerance test (ITT), standard-dose (250 μg) ACTH test (SDT) and low-dose (1 μg) ACTH test (LDT) Read More
A novel, non-functional, COL1A1 polymorphism is not associated with lumbar disk disease in young male Greek subjects unlike that of the Sp1 site
Thalia Bei2*, Constantinos Tilkeridis1*, Stavros Garantziotis3, Sosipatros A. Boikos2, Konstantinos Kazakos1, Constantinos Simopoulos1, Constantine A. Stratakis2 1“Democritus” University of Thrace, Alexandroupolis, Greece, 2Section on Genetics and Endocrinology, Program on Developmental Endocrinology & Genetics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA, 3Center for Recruitment of Military Personnel for Read More
The response of corticotropin and adrenal steroids to desmopressin stimulation in patients with various forms of hypercortisolism
Eugenia I. Marova, Nikolay P. Goncharov, Galina S. Kolesnikova, Svetlana D. Arapova, Anastasiya M. Lapshina National Research Center for Endocrinology of the Russian Academy of Medical Sciences, Moscow, Russia Abstract OBJECTIVE: The purpose of this study was to evaluate the direct action of desmopressin (agonist of vasopressin) on the hypophysis and the three zones of Read More
Pituitary-adrenal responses following major abdominal surgery
Ioanna Dimopoulou1, Marinella Tzanela2, Dimitra Vassiliadi2, Irini Mavrou1, Petros Kopterides1, Stylianos Orfanos1, Anastasia Kotanidou3, Styliani Kontogiannopoulou4, Spyridon Vasdekis5, Iraklis Tsangaris1, Apostolos Armaganidis1, Anastasios Macheras5, Ioannis Ilias6, Georgia Kostopanagiotou4, Stylianos Tsagarakis7 12nd Department of Critical Care Medicine, “Attikon” Hospital, Athens University School of Medicine, 2Department of Endocrinology, 31st Department of Critical Care Medicine, “Evangelismos” General Hospital, Read More
Pre- and early post-partum adiponectin and Interleukin-1beta levels in women with and without gestational diabetes
Nikolaos Vitoratos1, Georgios Valsamakis1,2, George Mastorakos1,2, Anastassios Boutsiadis1,2, Nikolaos Salakos1, Evagelia Kouskouni3, George Creatsas1 12nd Department of Obstetrics and Gynecology, 2Endocrine Unit, 3Department of Clinical Biochemistry, “Aretaieion” University Hospital, Athens University Medical School, Athens, Greece Abstract OBJECTIVE: To investigate maternal serum adiponectin and Ιnterleukin-1beta (IL-1β) levels during the pre- and post-partum periods in pregnant women Read More
Androgen insensitivity syndrome: clinical features and molecular defects
Angeliki Galani, Sophia Kitsiou-Tzeli, Christalena Sofokleous, Emmanuel Kanavakis, Ariadni Kalpini-Mavrou Department of Medical Genetics, University of Athens, “Choremis” Research Laboratory, “Aghia Sophia” Children’s Hospital, Athens, Greece Abstract The end-organ resistance to androgens has been designated as Androgen Insensitivity Syndrome (AIS), an X-linked disorder caused by mutations in the Androgen Receptor (AR) gene. It is generally Read More
Dysfunction of the Hypothalamic-Pituitary-Adrenal axis in HIV infection and disease
Evangelia Zapanti1, Konstantinos Terzidis1, George Chrousos2 11st Department of Endocrinology, “Alexandra” Hospital, Athens, 2Endocrine Unit, Department of Pediatrics, Athens University School of Medicine, “Aghia Sophia” Children’s Hospital, Athens, Greece Abstract Abnormalities of the Hypothalamic-Pituitary-Adrenal (HPA) axis have been documented in HIV patients in the early as well as late stages of the infection and range Read More