Gideon de Sousa, Rainer Wunsch, Werner Andler Vestische Kinder, Jugendklinik Datteln, University of Witten/Herdecke, Datteln, Germany Abstract We report the findings and clinical course of ten girls aged 0.2 to 6.3 years with precocious pseudopuberty due to autonomous ovarian cysts. We found elevated oestrogen levels in five patients and failure of gonadotropin response to GnRH Read More
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Autonomously functioning thyroid nodule treated with radioactive iodine and later diagnosed as papillary thyroid cancer
Mehmet Uludag,1 Gurkan Yetkin,1 Bulent Citgez,1 Adnan Isgor,2 Tulay Basak3 1Department of 2nd General Surgery, Sisli Etfal Training and Research Hospital, Sisli, 2Golden Horn University, Aksaray, 3Department of Pathology, Sisli Etfal Training and Research Hospital, Sisli, Istanbul, Turkey Abstract The malignancy risk is low in hot thyroid nodules verified by scintigraphy. We present a rare Read More
Rosiglitazone-induced anasarca without heart failure: capillary leakage?
Selcuk Dagdelen,1 Mevlut Kurt,2 Kadriye Aydιn,2 Miyase Bayraktar1 1Hacettepe University School of Medicine, Departments of Endocrinology and Metabolism, 2Internal Medicine, Ankara, Turkey Abstract Severity of thiazolidinedione (Rosiglitazone)-induced fluid retention is linked almost exclusively to cardiac decompensation. We here report a 68-year old female with type 2 diabetes mellitus, in whom a life-threatening (anasarca type) acute Read More
Highlights from the history of hormonal cytology
Aristidis Diamantis1, George Androutsos2 1Department of Cytopathology, Naval Hospital of Athens, Athens, 2Department of History of Medicine, Ioannina University School of Medicine, Ioannina, Greece Abstract In 1847 Felix-Archimede Pouchet effectively launched the study of the physiology of cytology. Now 160 years later, the authors briefly trace the development of hormonal cytology to our present knowledge Read More
The liaison of the young endocrine patient with the adult endocrinologist. On the occasion of a prismatic case
Editorial The case presented by Petzold et al in this issue1 highlights certain critical aspects of management of the child and adolescent with endocrine problems which are both of theoretical and practical interest. First, the discrepancy between the hormonal profile and the clinical manifestations, as described in this case, although not novel are, nevertheless, Read More
Dysfunction of the Hypothalamic-Pituitary-Adrenal axis in HIV infection and disease
Evangelia Zapanti1, Konstantinos Terzidis1, George Chrousos2 11st Department of Endocrinology, “Alexandra” Hospital, Athens, 2Endocrine Unit, Department of Pediatrics, Athens University School of Medicine, “Aghia Sophia” Children’s Hospital, Athens, Greece Abstract Abnormalities of the Hypothalamic-Pituitary-Adrenal (HPA) axis have been documented in HIV patients in the early as well as late stages of the infection and range Read More
Androgen insensitivity syndrome: clinical features and molecular defects
Angeliki Galani, Sophia Kitsiou-Tzeli, Christalena Sofokleous, Emmanuel Kanavakis, Ariadni Kalpini-Mavrou Department of Medical Genetics, University of Athens, “Choremis” Research Laboratory, “Aghia Sophia” Children’s Hospital, Athens, Greece Abstract The end-organ resistance to androgens has been designated as Androgen Insensitivity Syndrome (AIS), an X-linked disorder caused by mutations in the Androgen Receptor (AR) gene. It is generally Read More
Pre- and early post-partum adiponectin and Interleukin-1beta levels in women with and without gestational diabetes
Nikolaos Vitoratos1, Georgios Valsamakis1,2, George Mastorakos1,2, Anastassios Boutsiadis1,2, Nikolaos Salakos1, Evagelia Kouskouni3, George Creatsas1 12nd Department of Obstetrics and Gynecology, 2Endocrine Unit, 3Department of Clinical Biochemistry, “Aretaieion” University Hospital, Athens University Medical School, Athens, Greece Abstract OBJECTIVE: To investigate maternal serum adiponectin and Ιnterleukin-1beta (IL-1β) levels during the pre- and post-partum periods in pregnant women Read More
Pituitary-adrenal responses following major abdominal surgery
Ioanna Dimopoulou1, Marinella Tzanela2, Dimitra Vassiliadi2, Irini Mavrou1, Petros Kopterides1, Stylianos Orfanos1, Anastasia Kotanidou3, Styliani Kontogiannopoulou4, Spyridon Vasdekis5, Iraklis Tsangaris1, Apostolos Armaganidis1, Anastasios Macheras5, Ioannis Ilias6, Georgia Kostopanagiotou4, Stylianos Tsagarakis7 12nd Department of Critical Care Medicine, “Attikon” Hospital, Athens University School of Medicine, 2Department of Endocrinology, 31st Department of Critical Care Medicine, “Evangelismos” General Hospital, Read More
The response of corticotropin and adrenal steroids to desmopressin stimulation in patients with various forms of hypercortisolism
Eugenia I. Marova, Nikolay P. Goncharov, Galina S. Kolesnikova, Svetlana D. Arapova, Anastasiya M. Lapshina National Research Center for Endocrinology of the Russian Academy of Medical Sciences, Moscow, Russia Abstract OBJECTIVE: The purpose of this study was to evaluate the direct action of desmopressin (agonist of vasopressin) on the hypophysis and the three zones of Read More