Malignant struma ovarii harboring a unique NRAS mutation: case report and review of the literature

Carlo Gobitti,1 Alessandro Sindoni,2 Chiara Bampo,2 Tanja Baresic,2 Giorgio Giorda,3 Lara Alessandrini,4 Vincenzo Canzonieri,4 Giovanni Franchin,1 Eugenio Borsatti2 1Division of Radiotherapy, Centro di Riferimento Oncologico, IRCCS-National Cancer Institute, Aviano, PN Italy; 2Unit of Nuclear Medicine, Centro di Riferimento Oncologico, IRCCS-National Cancer Institute, Aviano, PN Italy; 3Gynecological Oncology Unit, Centro di Riferimento Oncologico, IRCCS-National Cancer Institute, Read More

A case of idiopathic granulomatous hypophysitis

Nilufer Ozdemir Kutbay,1 Mustafa Berker,2 Figen Soylemezoglu,3 Hatice Ozisik,4 Banu Sarer Yurekli4 1University of Health Sciences Gazi Yasargil Education and Training Hospital, Division of Endocrinology, Diyarbakır, Turkey; 2Acibadem Hospital, Department of Neurosurgery, Ankara, Turkey; 3Hacettepe University, Faculty of Medicine, Pathology Department, Ankara, Turkey; 4Ege University, Faculty of Medicine, Endocrinology Department, Izmir, Turkey   Dear Sir, Read More

Menophila: a poetic description of genital ambiguity in Hellenistic literature

Anastasia K. Armeni,1 Danai Georgakopoulou,1 Georgios K. Markantes, 1 Konstantina Barouti,1 Leonidas Liarakos,1 Vasiliki Vasileiou,2 Neoklis A. Georgopoulos1 1Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, University of Patras, Medical School, Patras, Greece; 21st Department of Endocrinology, Diabetes Centre, “Alexandra” Hospital, Athens, Greece Dear Sir, In Ancient Greece, up to the Classical era, hermaphrodites Read More

Endocrine sequelae of immune checkpoint inhibitors

Georgia Ntali,¹ Eva Kassi,2,3 Maria Alevizaki3,4 1Department of Endocrinology, Diabetes and Metabolism, Evangelismos Hospital, Athens, Greece; 2Department of Biological Chemistry, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece; 3Endocrine Unit, Department of Medical Therapeutics, Alexandra Hospital, Athens University School of Medicine, Athens, Greece; 4Endocrine Unit, Athens University, Evgenideion Hospital, Athens, Greece Abstract Read More

Diabetic nephropathy: is it always there? Assumptions, weaknesses and pitfalls in the diagnosis

Kyriakos Ioannou Department of Nephrology, American Medical Center, Nicosia, Cyprus; Department of Nephrology, Apollonion Private Hospital, Nicosia, Cyprus; European University School of Medicine, Nicosia, Cyprus Abstract Diabetic nephropathy is defined as a microvascular complication of the kidneys induced by diabetes mellitus and is characterized by albuminuria and progressive loss of kidney function. However, neither albuminuria Read More

Detection rate of somatostatin receptor PET in patients with recurrent medullary thyroid carcinoma: a systematic review and a meta-analysis

Giorgio Treglia,1,2,3* Adriana Tamburello,1* Luca Giovanella1 1Nuclear Medicine and PET/CT Center, Oncology Institute of Southern Switzerland, Bellinzona and Lugano, Switzerland; 2Health Technology Assessment Unit, General Directorate, Ente Ospedaliero Cantonale, Bellinzona, Switzerland; 3Nuclear Medicine and Molecular Imaging, CHUV University Hospital, Lausanne, Switzerland *GT and AT equally contributed to this article sharing the first authorship. Abstract PURPOSE: Read More

Prevalence, pathogenesis and management of prediabetes and type 2 diabetes mellitus in patients with polycystic ovary syndrome

Sofia Lazaridou,1 Konstantinos Dinas,2 Konstantinos Tziomalos1 1First Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece; 2Second Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece Abstract Polycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age. PCOS is Read More

Differentiated thyroid cancer in childhood: a literature update

Olga Karapanou,1 Marinella Tzanela,1 Barbara Vlassopoulou,1 Christina Kanaka-Gantenbein2 1Department of Endocrinology, Diabetes and Metabolism, “Evangelismos” Hospital, Athens, Greece; 2Division of Endocrinology, Metabolism and Diabetes, First Department of Pediatrics, “Aghia Sophia” Children’s Hospital, Athens, Greece Abstract Differentiated thyroid cancer in childhood is rare. Apart from family history, radiation exposure is a major risk factor. Although its Read More

Surgery for pheochromocytoma: A 20-year experience of a single institution

Chrysanthi Aggeli,1 Alexander M. Nixon,1 Christos Parianos,1 Georgios Vletsis,1 Labrini Papanastasiou,2 Athina Markou,2 Theodora Kounadi,2 Georgrios Piaditis,2 Georgios N. Zografos1 1Third Department of Surgery, Athens General Hospital “G. Gennimatas”, Greece; 2Department of Endocrinology and Diabetes Center, Athens General Hospital “G. Gennimatas”, Greece Abstract OBJECTIVE: Resection of pheochromocytomas is a challenging procedure due to hemodynamic lability. Read More

Baseline glucose homeostasis predicts the new onset of diabetes during statin therapy: A retrospective study in real life

Maria Chantal Ponziani,1 Ioannis Karamouzis,1 Chiara Mele,1,2 Luisa Chasseur,1 Marco Zavattaro,1 Marina Caputo,1 Maria Teresa Samà,1 Arianna Busti,1 Loredana Pagano,1 Luigi Castello,1 Paolo Marzullo,1,2 Gianluca Aimaretti,1 Flavia Prodam3 1Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy; 2Division of General Medicine, Istituto Auxologico Italiano, Ospedale S. Giuseppe, Piancavallo (VB), Italy; 3Department of Health Sciences, Read More