Serum fetuin-A levels are associated with serum triglycerides before and 6 months after bariatric surgery

Christos G. Verras,1 Georgios A. Christou,2 Yannis V. Simos,2 George D. Ayiomamitis,3 Andreas J. Melidonis,1 Dimitrios N. Kiortsis2 1Diabetes Center, Tzanio General Hospital, Piraeus, Greece, 2Laboratory of Physiology, Medical School, University of Ioannina, Ioannina, Greece, 32nd Department of Surgery, Tzanion General Hospital, Piraeus, Greece Abstract OBJECTIVE: The elucidation of the changes of fetuin-A in the Read More

The adrenal gland microenvironment in health, disease and during regeneration

Waldemar Kanczkowski,1 Mariko Sue,1 Stefan R. Bornstein1,2 1Department of Internal Medicine III, Technische Universität Dresden, Dresden, Germany, 2Department of Endocrinology and Diabetes, King’s College London, London, UK Abstract The adrenal gland is a key component of the stress system in the human body. Multiple direct and paracrine interactions between different cell types and their progenitors Read More

The Pineal Gland and its earliest physiological description

Konstantinos Laios Medical School, National and Kapodistrian University of Athens, Greece Dear Editor, The earliest physiological description of the Pineal (Latin: pinea = pinecone) Gland (also occasionally “conarium”, from the Greek: κωνάριο = κώνος = cone, pinecone) is found in two medical works written by Galen (2nd c. AD) (Figure 1). These works contain its Read More

Gut microbiota and obesity: implications for fecal microbiota transplantation therapy

Yongbo Kang,1,2,* Yue Cai1,3,* 1Medical Faculty, Kunming University of Science and Technology, Kunming, Yunnan, China; 2Genetics and Pharmacogenomics Laboratory, Kunming University of Science and Technology, Kunming, Yunnan, China; 3Pathogen biology Laboratory, Kunming University of Science and Technology, Kunming, Yunnan, China *Equal contributors Abstract Obesity is a major public health issue as it is causally associated Read More

Regulation of basal metabolic rate in uncomplicated pregnancy and in gestational diabetes mellitus

Eleftheria Taousani,1,2 Dimitra Savvaki,1 Efrosini Tsirou,1 Pavlos Poulakos,1 Gesthimani Mintziori,1 Menelaos Zafrakas,2 Basil C. Tarlatzis,1 Dimitrios Vavilis,1 Dimitrios G. Goulis1 1Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece; 2Department of Midwifery, Alexander Technological Educational Institute of Thessaloniki, Sindos, Greece Abstract Basal metabolic rate (BMR) is Read More

Ketogenic diet and testosterone increase: Is the increased cholesterol intake responsible? To what extent and under what circumstances can there be benefits?

Heitor Oliveira Santos School of Medicine, Federal University of Uberlandia (UFU), Uberlandia, Minas Gerais, Brazil DIETARY CHOLESTEROL FROM THE KETOGENIC DIET: IS IT A NEW SOURCE OF INCREASED TESTOSTERONE? The new study by Jacob Wilson et al. demonstrated that a nutritional intervention based on the ketogenic diet (KD) in resistance-trained athletes of college age showed Read More

Adiponectin levels may help assess the clinical repercussions of obesity irrespective of body mass index

Eirini Dermitzaki,1 Pavlina D. Avgoustinaki,1 Eirini C. Spyridaki,1,2 Panagiotis Simos,2,3 Niki Malliaraki,1 Maria Venihaki,1 Christos Tsatsanis,1 Andrew N. Margioris1 1Dept of Clinical Chemistry, School of Medicine, University of Crete, Heraklion, Crete; 2Dept of Psychiatry, School of Medicine, University of Crete, Heraklion, Crete; 3Computational BioMedicine Laboratory, Institute of Computer Science, Foundation of Research and Technology-Hellas; Greece Read More

Maternal serum placental growth hormone, insulin-like growth factors and their binding proteins at 20 weeks’ gestation in pregnancies complicated by gestational diabetes mellitus

Shutan Liao,1,2,5 Mark H. Vickers,1,2 Rennae S. Taylor,3 Mhoyra Fraser,4 Lesley M.E. McCowan,3 Philip N. Baker,1,2,6 Jo K. Perry1,2 1Liggins Institute, University of Auckland, Auckland, New Zealand; 2Gravida: National Centre for Growth and Development, New Zealand; 3Department of Obstetrics and Gynaecology, University of Auckland, Auckland, New Zealand; 4Department of Physiology, University of Auckland, Auckland, New Read More

Pegvisomant-primed growth hormone (GH) stimulation test is useful in identifying true GH deficient children

Giorgio Radetti,1 Heba H. Elsedfy,2 Randa Khalaf,2 Cristina Meazza,3 Sara Pagani,3 Mohamed El Kholy,2 Riccardo Albertini,4 Anna Maria De Stefano,5 Antonella Navarra,5 Annalisa De Silvestri,6 Mauro Bozzola3 1Marienklinik, Bolzano, Italy; 2Department of Paediatrics Ain Shams University, Cairo, Egypt; 3Department of Internal Medicine and Therapeutics, Pediatrics and Adolescentology Unit, University of Pavia, Fondazione IRCCS Policlinico San Read More

An insight into familial hypercholesterolemia in Greece: rationale and design of the Hellenic Familial Hypercholesterolemia Registry (HELLAS-FH)

Christos V. Rizos,1 Vasilios Athyros,2 Eleni Bilianou,3 George Chrousos,4 Anastasia Garoufi,5 Genovefa Kolovou,6 Vasilios Kotsis,7 Loukianos Rallidis,8 Emmanouel Skalidis,9 Ioannis Skoumas,10 Konstantinos Tziomalos,11 Evangelos N. Liberopoulos1 1Department of Internal Medicine, University of Ioannina Medical School, University Hospital of Ioannina, Ioannina, Greece; 2Department of Internal Medicine, Aristotle University of Thessaloniki Medical School, Hippokration Hospital, Thessaloniki, Greece; Read More