Polyzois Makras,1 Georgios Toloumis,1 Dimitrios Papadogias,2 Gregory A. Kaltsas,3,4 Michael Besser4 1Department of Endocrinology & Diabetes, 251 Hellenic Air Force General Hospital, Athens, Greece, 2Department of Endocrinology & Diabetes, “IASO” General Hospital, Athens, Greece, 3Department of Pathophysiology, National University of Athens, Athens, Greece, 4Department of Endocrinology, St Bartholomew’s Hospital, London, United Kingdom Abstract Cushing’s syndrome Read More
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Improvement of insulin sensitivity in patients with type 2 diabetes mellitus after oral administration of alpha-lipoic acid
Petya Kamenova Department of Diabetology, University Hospital of Endocrinology, Medical University, Sofia, Bulgaria Abstract BACKGROUND: Amelioration of insulin resistance could improve both glycaemic control and cardiovascular risk factors in patients with type 2 diabetes mellitus. Alpha-lipoic acid has been shown to improve insulin action after parenteral administration. OBJECTIVE: the aim of the study was to Read More
Effect of weight loss with or without orlistat treatment on adipocytokines, inflammation, and oxidative markers in obese women
Maria Bougoulia, Athanassios Triantos, George Koliakos Biochemistry Department, Aristoteles University Medical School, Thessaloniki, Greece Abstract OBJECT IVE: T he aim of this study was to evaluate the levels of adipose tissue related hormones, cytokines, and antioxidative substances in obese women before and after intervention with diet alone or with diet plus an inhibitor of gastrointestinental Read More
Total parathyroidectomy with autotransplantation in patients with renal hyperparathyroidism: indications and surgical approach
Stavros Gourgiotis, Panagiotis Moustafellos, Charalabos Stratopoulos, Vasilis Vougas, Spiros Drakopoulos, Evangelos Hadjiyannakis First Surgical Department – Organ Transplant Unit, "Evangelismos" General Hospital Athens, Greece Abstract OBJECTIVE: renal hyperparathyroidism (rH) is one of the most serious complications in long-term hemodialysis patients. the purpose of this retrospective study was the evaluation of the surgical indications, parathyroid histology, Read More
Iodine 131 treatment for differentiated thyroid carcinoma in patients with end stage renal failure: dosimetric, radiation safety, and practical considerations
Caliope Alevizaki,1 Michael Molfetas,1 Alexandros Samartzis,1 Barbara Vlassopoulou,2 Charalambos Vassilopoulos,2 Phoedi Rondogianni,3 Sofia Kottou,4 Valsamis Hadjiconstantinou,5 Maria Alevizaki6 1Medical Physics Laboratory, 2Endocrinology Department, 3Nuclear Medicine Department and 5Nephrology Department, Evangelismos Hospital Athens, 4Department of Medical Physics, Athens University School of Medicine and 6Endocrine Unit, Evgenideion Hospital, Athens University School of Medicine Abstract BACKGROUND: Iodine 131 Read More
A novel splicing mutation in exon 4 (456G>A) of the GH1 gene in a patient with congenital isolated growth hormone deficiency
Olga V. Fofanova,1 Oleg V. Evgrafov,2 Alexander V. Polyakov,2 Valentina A. Peterkova,1 Ivan I. Dedov1 1Institute of Pediatric Endocrinology, Endocrinology Research Center, Russian Academy of Medical Sciences, Moscow, 2DNA-Diagnostics Laboratory, Research Center for Medical Genetics, Russian Academy of Medical Sciences, Moscow, Russia Abstract Isolated Growth Hormone Deficiency (IGHD) due to GH1 gene defects has a Read More
Follicular carcinoma of the thyroid with aggressive metastatic behavior in a pregnant woman: Report of a case and review of the literature
Luciana Parlea, Lisa Fahim, David Munoz, Amir Hanna, Jennifer Anderson, Michael Cusimano, Kalman Kovacs, Geoffrey Gardiner Departments of Medicine (LP, AH), Laboratory Medicine, (LF, DM, KK, GG), and Surgery (JA, MC) at St. Michael’s Hospital, University of Toronto, Toronto, ON, Canada Abstract Distant metastases as initial presentation of follicular carcinoma of the thyroid is rare, Read More
Papillary thyroid carcinoma producing granulocyte-macrophage colony-stimulating factor is associated with neutrophilia and eosinophilia
Evangeline Vassilatou1, Markos Fisfis2, George Morphopoulos3, Sotiria Savva3, Eugenia Voucouti4, Katerine Stefanoudaki2, Ioanna Tzavara1 1Department of Endocrinology, Diabetes and Metabolism, 2Department of Haematology and 3Department of Histopathology, “A. Fleming” General Hospital, Athens, Greece and 4Laboratory of Haematology, “G. Gennimatas” General Hospital, Athens, Greece Abstract Thyroid tumors producing colony-stimulating factors associated with neutrophilia and/or eosinophilia are Read More
Oskar Minkowski (1858-1931). An outstanding master of diabetes research
Victor Jörgens* Executive Director, EASD/EFSD, Düsseldorf, Germany Abstract Oskar Minkowski, a physician of many talents, was an outstanding clinical scientist, a brilliant experimental investigator and a prolific medical writer. His name is connected with highly important clinical studies and experimental probes, all of which significantly contributed to our understanding of the pathogenesis of diabetes mellitus Read More
Coronary heart disease in postmenopausal women; the role of endogenous estrogens and their receptors
Katerina Saltiki, Maria Alevizaki Endocrine Unit, Evgenidion Hospital and Department Medical Therapeutics, Alexandra Hospital, Athens University School of Medicine, Athens 11528, Greece Abstract Coronary heart disease is the main cause of death in women. Women during reproductive years are at lower risk for coronary heart disease than men but this difference tends to disappear after Read More